SCHEMBL83918

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25142073	0.78	HRH4 (0.43)	OGACYP17A1ALDH1A1EGLN2HTT
	SCHEMBL82390	0.78	MMP2 (0.38)	MMP2ADAMTS5OGACYP17A1ALDH1A1
	SCHEMBL82388	0.78	MMP2 (0.38)	MMP2ADAMTS5OGACYP17A1ALDH1A1
	SCHEMBL82389	0.78	MMP2 (0.38)	MMP2ADAMTS5OGACYP17A1ALDH1A1
	SCHEMBL82677	0.78	MMP2 (0.38)	MMP2ADAMTS5OGACYP17A1ALDH1A1
	SCHEMBL82676	0.78	MMP2 (0.38)	MMP2ADAMTS5OGACYP17A1ALDH1A1
	SCHEMBL17884822	0.75	MMP2 (0.42)	MMP2ADAMTS5
	SCHEMBL16382029	0.74	OGA (0.39)	MMP2ADAMTS5OGACYP17A1ALDH1A1
	SCHEMBL23554366	0.73	LRRK2 (0.34)	MMP2ADAMTS5OGACYP17A1PRCP
	SCHEMBL22796061	0.73	MAP4K4 (0.49)	ALDH1A1PRCPL3MBTL1HTTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.