Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | GBA1 | P04062 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | BMP1 | P13497 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623889 | 1.00 | ALDH1A1 (0.60) | ALDH1A1PKMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8392223 | 0.98 | ALDH1A1 (0.62) | ALDH1A1PKMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8394130 | 0.95 | ALDH1A1 (0.62) | ALDH1A1PKMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8395503 | 0.92 | ALDH1A1 (0.66) | ALDH1A1PKMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8397048 | 0.91 | GBA1 (0.58) | ALDH1A1PKMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8391910 | 0.91 | GBA1 (0.58) | ALDH1A1PKMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8393373 | 0.89 | GBA1 (0.60) | ALDH1A1PKMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8391575 | 0.86 | GBA1 (0.60) | ALDH1A1PKMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8394585 | 0.82 | GBA1 (0.69) | ALDH1A1PKMKDM4ELMNASMN1; SMN2 | |
| SCHEMBL29183284 | 0.82 | ALDH1A1 (0.67) | ALDH1A1PKMLMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |