Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8392155 | 0.89 | TYR (0.40) | TYRCYP3A4CYP2C9CYP1A2TSHR | |
| SCHEMBL11261908 | 0.80 | CYP1A2 (0.37) | TYRCYP3A4CYP2C9CYP1A2TSHR | |
| SCHEMBL2332261 | 0.78 | CA1 (0.39) | CYP3A4TSHRCYP2C19APEX1ALDH1A1 | |
| SCHEMBL9512505 | 0.76 | APEX1 (0.38) | CYP1A2TSHRCYP2C19APEX1ALDH1A1 | |
| SCHEMBL10413283 | 0.74 | TYR (0.38) | TYRTACR1LMNA | |
| SCHEMBL11252515 | 0.73 | CYP2C19 (0.35) | TYRCYP3A4CYP2C9CYP1A2TSHR | |
| SCHEMBL10413317 | 0.72 | APEX1 (0.34) | APEX1 | |
| SCHEMBL8395785 | 0.71 | CA1 (0.39) | CYP3A4CYP2C19APEX1ALDH1A1NR1I2 | |
| SCHEMBL11867420 | 0.71 | TYR (0.65) | TYRCYP3A4CYP2C9CYP1A2TSHR | |
| SCHEMBL10413325 | 0.70 | TYR (0.39) | TYRCYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36128-E | STABILIZER FOR ORGANIC COMPOUNDS | ALBEMARLE CORPORATION (US) | 1999-03-02 | — | — | US | disclosed |
| EP-0280938-B1 | Antioxidant aromatic fluorophosphites | ETHYL CORP (US) | 1994-06-15 | — | — | EP | disclosed |
| US-4912155-A | Containing substituted aryl group | ETHYL CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| EP-0280938-A1 | Antioxidant aromatic fluorophosphites | ALBEMARLE CORPORATION (US) | 1988-09-07 | — | — | EP | disclosed |