Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252515 | 0.82 | CYP2C19 (0.35) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL11267743 | 0.82 | TSHR (0.38) | TSHRCYP2C19APEX1TYRUSP2 | |
| SCHEMBL11249531 | 0.81 | GAA (0.33) | USP2MAPT | |
| SCHEMBL8392149 | 0.80 | TYR (0.42) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL11244840 | 0.79 | TYR (0.34) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL10442707 | 0.78 | TYR (0.37) | TYRLMNAESR1CHRM2CHRM4 | |
| SCHEMBL7952152 | 0.78 | TYR (0.37) | TYRLMNAESR1CHRM2CHRM4 | |
| SCHEMBL8392155 | 0.78 | TYR (0.40) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL29878455 | 0.78 | ALDH1A1 (0.39) | CYP3A4CYP2C19APEX1TYRLMNA | |
| SCHEMBL295242 | 0.78 | ALDH1A1 (0.39) | CYP3A4CYP2C19APEX1TYRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346025-A | Stabilized vinyl chloride polymer comprising a phenylethylidene aryl phosphite | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1982-08-24 | — | — | US | disclosed |