SCHEMBL839232

SCHEMBL839232

[CH2]Cc1ccccc1CC

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.46
GABRB2 P47870 4/20 0.46
MGLL Q99685 1/20 0.41
TP53 P04637 2/20 0.39
MAPT P10636 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP2D6 P10635 1/20 0.36
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
CTSB P07858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL7684069 0.85 GABRA1 (0.52) GABRA1GABRB2MGLLTP53MAPT
SCHEMBL132297 0.85 HSPA5 (0.38) CYP2D6
SCHEMBL36294 0.85 GABRA1 (0.58) GABRA1GABRB2MGLLTP53MAPT
SCHEMBL25425763 0.85 GABRA1 (0.58) GABRA1GABRB2MGLLTP53MAPT
SCHEMBL29390847 0.85 GABRA1 (0.58) GABRA1GABRB2MGLLTP53MAPT
Benzene SCHEMBL3122858 0.82 TP53 (0.56) GABRA1GABRB2MGLLTP53MAPT
SCHEMBL7542830 0.82 GABRA1 (0.55) GABRA1GABRB2MGLLTP53MAPT
SCHEMBL14807864 0.82 GABRA1 (0.55) GABRA1GABRB2MGLLTP53MAPT
Ammonia Solution, Strong SCHEMBL2638008 0.82 GABRA1 (0.55) GABRA1GABRB2MGLLTP53MAPT
Benzene SCHEMBL11603070 0.82 TP53 (0.56) GABRA1GABRB2MGLLTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112867706-A MASP-2 inhibitors and methods of use 奥默罗斯公司 2021-05-28 CN claimed
EP-3802489-A2 MASP-2 INHIBITORS AND METHODS OF USE Omeros Corporation (US) 2021-04-14 EP claimed
US-9943501-B2 PPAR-gamma activator KOJUN JAPAN CO., LTD. (JP) 2018-04-17 US claimed
EP-3167883-A1 PPARy ACTIVATING AGENT Kojun Japan Co. Ltd. (JP) 2017-05-17 EP claimed
US-20170105965-A1 PPAR-gamma ACTIVATOR KOJUN JAPAN CO., LTD. (JP) 2017-04-20 US claimed
CN-102584829-A Pyrazole and pyrazine diketone derivative and application thereof UNIV SHANDONG 2012-07-18 CN claimed
CN-101367819-B 5-substituent-2-(4-substituted phenyl)-6,7-dihydrogen pyrazole-[1,5-a]pyrazine-4(5H)-ketone derivant and uses thereof UNIV SHANDONG 2010-08-18 CN claimed
CN-101633675-A Preparation and application of 5-substituent group-6-substituent phenyl-2-ferrocenyl pyrazolo [1, 5-a] pyrazine-4(5H)-ketone derivative UNIV SHANDONG 2010-01-27 CN claimed
CN-101367819-A 5-substituent-2-(4-substituted phenyl)-6,7-dihydrogen pyrazole-[1,5-a]pyrazine-4(5H)-ketone derivant and uses thereof UNIV SHANDONG (CN) 2009-02-18 CN claimed
US-7304086-B2 Inhibitors of glutaminyl cyclase PROBIODRUG AG (DE) 2007-12-04 US claimed
CN-1021281-C ORGANIC PHOSPHORUS PESTICIDE COMPOSITIONS STAUFFER CHEMICAL CO (US) 1993-06-23 CN claimed
US-3930671-A Color former and pressure-sensitive copying paper FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US claimed
CN-117964683-A MASP-2 inhibitors and methods of use 奥默罗斯公司 2024-05-03 CN disclosed
CN-117964684-A MASP-2 inhibitors and methods of use 奥默罗斯公司 2024-05-03 CN disclosed
US-11718758-B2 Aqueous dispersion of colored particles MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2023-08-08 US disclosed
EP-3725854-B1 COLORED PARTICLE AQUEOUS DISPERSION MITSUBISHI PENCIL CO (JP) 2023-07-05 EP disclosed
EP-0051391-A1 Bicyclic compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1982-05-12 EP disclosed
US-3996193-A POLYALKYLENEPOLYAMINES, DIOLEFIN RUBBER THE DOW CHEMICAL COMPANY (US) 1976-12-07 US disclosed
US-3971825-A (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS SANKYO COMPANY LIMITED (JA) 1976-07-27 US disclosed
US-3930671-A Color former and pressure-sensitive copying paper FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170105965-A1 PPAR-gamma ACTIVATOR PPARG, PPARA, PPARD GABRA1 244/4885GABRB2 165/4885MGLL 429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.