Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.59 |
| ▸ | ESR1 | P03372 | 4/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.55 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.55 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8391623 | 0.93 | RECQL (0.64) | ESR2ESR1RECQLGRIA1CACNG8 | |
| SCHEMBL8393566 | 0.89 | RECQL (0.56) | ESR2ESR1RECQLALDH1A1PPARG | |
| SCHEMBL8394776 | 0.85 | RECQL (0.58) | ESR2ESR1RECQLALDH1A1PPARG | |
| SCHEMBL8393582 | 0.85 | RECQL (0.56) | ESR2ESR1RECQLALDH1A1LMNA | |
| SCHEMBL8392446 | 0.85 | PTPN11 (0.51) | RECQLALDH1A1PPARGKDM4EABCC3 | |
| SCHEMBL8396869 | 0.84 | RECQL (0.60) | RECQLALDH1A1KDM4EHPGDMAPK1 | |
| SCHEMBL8391723 | 0.82 | RECQL (0.57) | ESR2ESR1RECQLALDH1A1PPARG | |
| SCHEMBL8393411 | 0.81 | RECQL (0.56) | RECQLALDH1A1PPARGKDM4EHPGD | |
| SCHEMBL8395931 | 0.81 | RECQL (0.55) | RECQLALDH1A1PPARGKDM4EHPGD | |
| SCHEMBL8392464 | 0.81 | RECQL (0.55) | RECQLALDH1A1LMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |