Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394776 | 0.89 | RECQL (0.58) | RECQLMAPK1HTTHSD17B10POLB | |
| SCHEMBL8391723 | 0.88 | RECQL (0.57) | RECQLMAPK1HTTHSD17B10KDM4E | |
| SCHEMBL8391623 | 0.88 | RECQL (0.64) | RECQLMAPK1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL3732608 | 0.87 | MAPK1 (0.59) | RECQLMAPK1HTTHSD17B10POLB | |
| SCHEMBL8393411 | 0.87 | RECQL (0.56) | RECQLMAPK1HSD17B10POLBKDM4E | |
| SCHEMBL8392464 | 0.86 | RECQL (0.55) | RECQLMAPK1HTTTSHRKDM4E | |
| SCHEMBL8395931 | 0.86 | RECQL (0.55) | RECQLMAPK1HTTPOLBKDM4E | |
| SCHEMBL8396019 | 0.86 | RECQL (0.55) | RECQLMAPK1HSD17B10POLBTSHR | |
| SCHEMBL8392677 | 0.84 | ESR2 (0.59) | RECQLMAPK1HSD17B10POLBKDM4E | |
| SCHEMBL8396962 | 0.84 | PPARG (0.55) | RECQLMAPK1HSD17B10POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |