Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8393126 | 1.00 | CRBN (0.38) | CRBNLMNAALDH1A1MAPTTHRA | |
| SCHEMBL7770228 | 0.87 | S1PR1 (0.40) | CRBNLMNAALDH1A1C3AR1 | |
| SCHEMBL7770231 | 0.87 | S1PR1 (0.40) | CRBNLMNAALDH1A1C3AR1 | |
| SCHEMBL8540890 | 0.86 | FFAR4 (0.38) | CYP1A2 | |
| SCHEMBL8540893 | 0.86 | FFAR4 (0.38) | CYP1A2 | |
| SCHEMBL8440138 | 0.84 | FFAR4 (0.39) | LMNAALDH1A1MAPTCYP2D6CYP2C19 | |
| SCHEMBL8440137 | 0.84 | FFAR4 (0.39) | LMNAALDH1A1MAPTCYP2D6CYP2C19 | |
| SCHEMBL8397589 | 0.83 | MAOB (0.36) | CRBNALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL7771011 | 0.82 | FFAR4 (0.40) | LMNAALDH1A1RAB9AC3AR1 | |
| SCHEMBL7771013 | 0.82 | FFAR4 (0.40) | LMNAALDH1A1RAB9AC3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650969-B1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5659059-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0650969-A1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-05-03 | — | — | EP | disclosed |