Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.82 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.82 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8393139 | 1.00 | ESR1 (0.82) | ESR1ESR2PTGS1PTGS2CYP19A1 | |
| SCHEMBL3988719 | 0.93 | ESR1 (0.82) | ESR1ESR2PTGS1PTGS2CYP19A1 | |
| SCHEMBL9622832 | 0.93 | ESR1 (0.82) | ESR1ESR2PTGS1PTGS2CYP19A1 | |
| SCHEMBL3988713 | 0.93 | ESR1 (0.82) | ESR1ESR2PTGS1PTGS2CYP19A1 | |
| SCHEMBL574346 | 0.90 | ESR1 (1.00) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL9113341 | 0.90 | ESR1 (1.00) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL1226484 | 0.88 | ESR1 (0.62) | ESR1ESR2PTGS1PTGS2CYP19A1 | |
| SCHEMBL5606420 | 0.88 | ESR1 (0.62) | ESR1ESR2PTGS1PTGS2CYP19A1 | |
| SCHEMBL7912475 | 0.88 | ESR1 (0.62) | ESR1ESR2PTGS1PTGS2CYP19A1 | |
| SCHEMBL10850323 | 0.85 | ESR1 (0.59) | ESR1ESR2PTGS1PTGS2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409069-B1 | Mesogenic polycyanates and polycyanamides and thermosets thereof | DOW CHEMICAL CO (US) | 1999-06-02 | — | — | EP | disclosed |
| EP-0409070-B1 | Mesogenic cyanite functional maleimides and thermosets thereof | DOW CHEMICAL CO (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5612479-A | Polyphenols containing mesogenic moieties as lateral substituents | THE DOW CHEMICAL COMPANY (US) | 1997-03-18 | — | — | US | disclosed |
| US-5470946-A | Products resulting from polymerizing or curing polycyanates containing mesogenic moieties as lateral substituents | THE DOW CHEMICAL COMPANY (US) | 1995-11-28 | — | — | US | disclosed |
| US-5442039-A | Rod-like mesogenic structures incorporated into polytriazine products; improved tensile strength, flexural strength | THE DOW CHEMICAL COMPANY (US) | 1995-08-15 | — | — | US | disclosed |
| US-5428125-A | Liquid crystalline | THE DOW CHEMICAL COMPANY (US) | 1995-06-27 | — | — | US | disclosed |
| US-5374769-A | Polycyanates containing mesogenic moieties as lateral substituents | THE DOW CHEMICAL COMPANY (US) | 1994-12-20 | — | — | US | disclosed |
| US-5248758-A | Curable composition | THE DOW CHEMICAL COMPANY (US) | 1993-09-28 | — | — | US | disclosed |
| US-5248757-A | Curable composition | THE DOW CHEMICAL COMPANY (US) | 1993-09-28 | — | — | US | disclosed |
| US-5206321-A | Polycyanates containing mesogenic moieties as lateral substituents | THE DOW CHEMICAL COMPANY (US) | 1993-04-27 | — | — | US | disclosed |
| US-5077380-A | Mesogenic cyanate functional maleimides and thermosets thereof | THE DOW CHEMICAL COMPANY (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0409069-A2 | Mesogenic polycyanates and thermosets thereof | THE DOW CHEMICAL COMPANY (US) | 1991-01-23 | — | — | EP | disclosed |
| EP-0409070-A2 | Mesogenic cyanite functional maleimides and thermosets thereof | THE DOW CHEMICAL COMPANY (US) | 1991-01-23 | — | — | EP | disclosed |