SCHEMBL574346

SCHEMBL574346

CCC(=Cc1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 1.00
ESR2 Q92731 4/20 1.00
PTGS1 P23219 9/20 0.59
PTGS2 P35354 5/20 0.56
NQO2 P16083 2/20 0.56
ALDH1A1 P00352 2/20 0.50
MEN1 O00255 1/20 0.50
NR1I2 O75469 1/20 0.50
USP2 O75604 1/20 0.50
LMNA P02545 1/20 0.50
NR3C1 P04150 1/20 0.50
TP53 P04637 1/20 0.50
CYP1A2 P05177 1/20 0.50
FYN P06241 1/20 0.50
PGR P06401 1/20 0.50
CHRM2 P08172 1/20 0.50
ADRB1 P08588 1/20 0.50
CYP3A4 P08684 1/20 0.50
ADRA2A P08913 1/20 0.50
ADORA3 P0DMS8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9113341 1.00 ESR1 (1.00) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL3988719 0.90 ESR1 (0.82) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL9622832 0.90 ESR1 (0.82) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL3988713 0.90 ESR1 (0.82) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL8393141 0.90 ESR1 (0.82) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL8393139 0.90 ESR1 (0.82) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL5692913 0.89 ESR1 (0.80) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL5692915 0.89 ESR1 (0.80) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL9258161 0.84 ESR1 (0.72) ESR1ESR2PTGS1PTGS2NQO2
SCHEMBL9258167 0.84 ESR1 (0.72) ESR1ESR2PTGS1PTGS2NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118995687-A Fe (Fe)3O4@Al3+Preparation of material immobilized laccase and application of material immobilized laccase in degradation of ethylstilbestrol 扬州大学 2024-11-22 CN claimed
CN-116539873-A Diethylstilbestrol detection method based on photothermal probe and lateral chromatography test paper 山东师范大学 2023-08-04 CN claimed
CN-116496407-A Double-function fusion protein and preparation method and application thereof 赋生康(上海)生物科技有限公司 2023-07-28 CN claimed
CN-116439198-A High-density breeding method for factory sheep raising 安徽省天长市周氏羊业有限公司 2023-07-18 CN claimed
WO-2022169634-A1 COMBINATION THERAPY FOR THE TREATMENT OF CANCER UNM RAINFOREST INNOVATIONS (US) 2022-08-11 WO claimed
WO-2021072473-A1 ANTIMICROBIALS AS FEED PRESERVATIVES IRP Health Pty Ltd (AU) 2021-04-22 WO claimed
WO-2018195202-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER PELLFICURE PHARMACEUTICALS INC. (US) 2018-10-25 WO claimed
US-20130219528-A1 NOVEL TREATMENT OF PROSTATE CARCINOMA PELLFICURE PHARMACEUTICALS, INC. (US) 2013-08-22 US claimed
EP-2600855-A2 COMBINATION THERAPY FOR THE TREATMENT OF PROSTATE CARCINOMA Pellficure Pharmaceuticals, Inc. (US) 2013-06-12 EP claimed
WO-2012018948-A2 NOVEL TREATMENT OF PROSTATE CARCINOMA PELLFICURE PHARMACEUTICALS, INC. (US) 2012-02-09 WO claimed
EP-2066679-A1 CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF AEterna Zentaris GmbH (DE) 2009-06-10 EP claimed
WO-2008028934-A1 CONJUGATES OF DISORAZOLES AND THEIR DERIVATIVES WITH CELL-BINDING MOLECULES, NOVEL DISORAZOLE DERIVATIVES, PROCESSES OF MANUFACTURING AND USES THEREOF AETERNA ZENTARIS GMBH (DE) 2008-03-13 WO claimed
WO-2003068229-A1 PYRIDINE, QUINOLINE, AND ISOQUINOLINE N-OXIDES AS KINASE INHIBITORS BAYER PHARMACEUTICALS CORPORATION (US) 2003-08-21 WO claimed
WO-1997032589-A1 COMBINATIONS FOR TREATMENT OF PROLIFERATIVE DISEASES NOVARTIS AG (CH) 1997-09-12 WO claimed
WO-1997032604-A1 ANTIPROLIFERATIVE COMBINATIONS, CONTAINING RAF-TARGETED OLIGONUCLEOTIDES AND CHEMOTHERAPEUTIC COMPOUNDS NOVARTIS AG (CH) 1997-09-12 WO claimed
CN-115368356-B Bicyclic heterocyclic compounds and therapeutic uses thereof 阿斯特克斯治疗有限公司 2025-05-09 CN disclosed
CN-118995687-A Fe (Fe)3O4@Al3+Preparation of material immobilized laccase and application of material immobilized laccase in degradation of ethylstilbestrol 扬州大学 2024-11-22 CN disclosed
US-5382693-A Curing agents for epoxy resins THE DOW CHEMICAL COMPANY (US) 1995-01-17 US disclosed
WO-1994026690-A1 BIS(AMINOPHENOXY)-ALPHA-SUBSTITUTED STILBENES, CURABLE MIXTURES WITH EPOXY RESINS AND CURED PRODUCTS THE DOW CHEMICAL COMPANY (US) 1994-11-24 WO disclosed
US-5300594-A Bis(aminophenoxy)-alpha-substituted stilbenes, curable mixtures with epoxy resins and cured products THE DOW CHEMICAL COMPANY (US) 1994-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130219528-A1 NOVEL TREATMENT OF PROSTATE CARCINOMA KLK3, AR, PLK1 ESR1 671/4885ESR2 486/4885PTGS1 369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.