SCHEMBL83934

SCHEMBL83934

Fc1c(Cl)ncnc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL793968 0.81
SCHEMBL1368468 0.81
SCHEMBL28384568 0.77 PDE4A (0.30)
SCHEMBL28378891 0.75 ALDH1A1 (0.31)
SCHEMBL1440229 0.75 PDPK1 (0.37)
SCHEMBL28133632 0.75
SCHEMBL15649019 0.75
SCHEMBL3638638 0.74
SCHEMBL31337546 0.74
SCHEMBL30391624 0.74 ALDH1A1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559483-B2 Process for the preparation of fluoxastrobin and intermediates thereof UPL LTD (IN) 2026-02-24 US claimed
CN-114853682-B Production equipment and method of crude drug intermediate 4, 6-dichloro-5-fluoropyrimidine 江苏中渊化学品有限公司 2024-07-26 CN claimed
US-20230219940-A1 PROCESS FOR THE PREPARATION OF FLUOXASTROBIN AND INTERMEDIATES THEREOF UPL LTD (IN) 2023-07-13 US claimed
CN-115916774-A Process for the preparation of fluoxastrobin and intermediates thereof UPL有限公司 2023-04-04 CN claimed
CN-114874147-A Preparation method of 4, 6-dichloro 5-fluoropyrimidine 江苏中渊化学品有限公司 2022-08-09 CN claimed
CN-114853682-A Production equipment and method of bulk drug intermediate 4, 6-dichloro-5-fluoropyrimidine 江苏中渊化学品有限公司 2022-08-05 CN claimed
WO-2021250558-A1 PROCESS FOR THE PREPARATION OF FLUOXASTROBIN AND INTERMEDIATES THEREOF UPL LIMITED (IN) 2021-12-16 WO claimed
EP-1533303-B1 Substituted Aminosalicylacid Amides ( intermediates ) BAYER CROPSCIENCE AG (DE) 2013-04-24 EP claimed
EP-2292608-A1 Intermediates for the preparation of substituted Aminosalicylic acid amides with fungicidal activity Bayer CropScience AG (DE) 2011-03-09 EP claimed
EP-1533303-A1 Substituted Aminosalicylacid Amides ( intermediates ) Bayer CropScience AG (DE) 2005-05-25 EP claimed
EP-1077210-B1 Preparation of 4,6-dichloro-5-fluorpyrimidine and its use as biocidally active agent BAYER CROPSCIENCE AG (DE) 2004-04-28 EP claimed
US-6380386-B2 INSECTICIDES, BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-04-30 US claimed
US-20020006958-A1 Substituted aminosalicylic acid amides with fungicidal effect and intermediate products for production thereof BAYER INTELLECTUAL PROPERTY GMBH (DE) 2002-01-17 US claimed
US-6255486-B1 REACTING 2-FLUOROPROPANEDIOIC ACID, DIALKYLESTER WITH ETHYL/ METHYL FLUOROMALONATE &amp; FORMAMIDE IN PRESENCE OF ALKALI METAL ALKOXIDES, THEN WITH PHOSPHOROUS OXYCHLORIDE AND CHLORINE IN PRESENCE OF PHOSPHOROUS TRICHLORIDE, PHOSPHATE-FREE BAYER AKTIENGESELLSCHAFT (DE) 2001-07-03 US claimed
EP-1077210-A2 Preparation of 4,6-dichloro-5-fluorpyrimidine and its use as biocidally active agent Bayer Aktiengesellschaft (DE) 2001-02-21 EP claimed
EP-4720064-A1 FUSED AZOLED AS TYK2 INHIBITORS AND USES THEREOF Sudo Biosciences Limited (GB) 2026-04-08 EP disclosed
CN-121648857-A Recovery device and process for triethylamine in 4, 6-dichloro-5-fluoropyrimidine production 福建永晶科技股份有限公司 2026-03-13 CN disclosed
WO-2000071504-A1 METHOD OF PRODUCING METHOXYIMINO ACETIC AMIDE BAYER AKTIENGESELLSCHAFT (DE) 2000-11-30 WO disclosed
EP-0970057-A2 SUBSTITUTED AMINOSALICYCLIC ACID AMIDES WITH FUNGICIDAL EFFECT AND INTERMEDIATE PRODUCTS FOR PRODUCTION THEREOF BAYER AG (DE) 2000-01-12 EP disclosed
WO-1998041513-A2 SUBSTITUTED AMINOSALICYCLIC ACID AMIDES WITH FUNGICIDAL EFFECT AND INTERMEDIATE PRODUCTS FOR PRODUCTION THEREOF BAYER AKTIENGESELLSCHAFT (DE) 1998-09-24 WO disclosed