Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.40 |
| ▸ | RARA | P10276 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433948 | 0.88 | MAPT (0.36) | HIF1AEPHX2MAPK1HPGDRECQL | |
| SCHEMBL8437028 | 0.88 | RARA (0.49) | IKBKBRARAEPHX2MAPK1CYP2C9 | |
| SCHEMBL8394253 | 0.86 | IKBKB (0.49) | IKBKBRARAHIF1AEPHX2MAPK1 | |
| SCHEMBL8693106 | 0.85 | IKBKB (0.57) | IKBKBRARAHIF1AEPHX2MAPK1 | |
| SCHEMBL8694721 | 0.79 | RARA (0.54) | IKBKBRARAHIF1AEPHX2MAPT | |
| SCHEMBL8457513 | 0.79 | RARA (0.49) | IKBKBRARAHIF1AEPHX2MAPK1 | |
| SCHEMBL8398267 | 0.76 | IKBKB (0.49) | IKBKBRARAHIF1AEPAS1 | |
| SCHEMBL8437023 | 0.75 | RARA (0.41) | IKBKBRARAEPHX2MAPK1RECQL | |
| SCHEMBL8693724 | 0.74 | RARA (0.57) | IKBKBRARAHIF1AEPAS1 | |
| SCHEMBL8436433 | 0.73 | RARA (0.34) | IKBKBRARAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776881-B1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CIRD GALDERMA (FR) | 1999-12-08 | — | — | EP | claimed |
| US-5877342-A | SKIN DISORDERS; RESPIRATORY SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUIES GALDERMA (FR) | 1999-03-02 | — | — | US | claimed |
| US-5877342-A | SKIN DISORDERS; RESPIRATORY SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUIES GALDERMA (FR) | 1999-03-02 | — | — | US | disclosed |