Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.56 |
| ▸ | RARA | P10276 | 4/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RARG | P13631 | 4/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888286 | 0.91 | RARA (0.64) | IKBKBRARAFDPSALDH1A1RARG | |
| SCHEMBL7690770 | 0.88 | RARA (0.54) | IKBKBRARAFDPSALDH1A1RARG | |
| SCHEMBL8433867 | 0.84 | RARA (0.74) | IKBKBRARARARGRARBLMNA | |
| SCHEMBL8614545 | 0.83 | IKBKB (0.58) | IKBKBRARAFDPSALDH1A1RARG | |
| SCHEMBL8435257 | 0.83 | IKBKB (0.48) | IKBKBRARARARGRARBHDAC11 | |
| SCHEMBL7920890 | 0.83 | RARA (0.51) | IKBKBRARAALDH1A1RARGRARB | |
| SCHEMBL8428529 | 0.83 | RARA (0.52) | IKBKBRARARARGRARBHDAC11 | |
| SCHEMBL6033341 | 0.82 | IKBKB (0.49) | IKBKBRARAALDH1A1RARGRARB | |
| SCHEMBL6033010 | 0.81 | IKBKB (0.48) | IKBKBRARAALDH1A1RARGRARB | |
| SCHEMBL8572262 | 0.81 | IKBKB (0.51) | IKBKBRARAALDH1A1RARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776881-B1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CIRD GALDERMA (FR) | 1999-12-08 | — | — | EP | disclosed |
| US-5877342-A | SKIN DISORDERS; RESPIRATORY SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUIES GALDERMA (FR) | 1999-03-02 | — | — | US | disclosed |
| EP-0776881-A1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1997-06-04 | — | — | EP | disclosed |