Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397065 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8392303 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8396790 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8395212 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8396609 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8396569 | 0.98 | MEN1 (0.55) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8393256 | 0.98 | L3MBTL1 (0.52) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8395938 | 0.98 | L3MBTL1 (0.52) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8393478 | 0.98 | MEN1 (0.55) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8391316 | 0.98 | L3MBTL1 (0.52) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |