SCHEMBL8395154

SCHEMBL8395154

CCCOC1C=CC(=O)O1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
PDCD4 Q53EL6 2/20 0.32
XPO1 O14980 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31592750 0.89 PDCD4 (0.36) PDCD4XPO1
SCHEMBL3877380 0.87 PDCD4 (0.38) ALDH1A1PDCD4
SCHEMBL8392681 0.86 GBA1 (0.41) ALDH1A1PDCD4
SCHEMBL8985123 0.86 GBA1 (0.41) ALDH1A1PDCD4
SCHEMBL15816687 0.83 TSHR (0.31)
SCHEMBL8392577 0.80 NFE2L2 (0.35) ALDH1A1PDCD4XPO1
SCHEMBL8393593 0.80 PDCD4 (0.32) PDCD4XPO1
SCHEMBL980478 0.73
SCHEMBL10581556 0.73
SCHEMBL8665317 0.72 NFE2L2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0761808-B1 Use of substituted lactones as perfuming agent HAARMANN & REIMER GMBH (DE) 1999-05-19 EP disclosed
EP-0761808-A2 Use of substituted lactones as perfuming agent HAARMANN & REIMER GMBH (DE) 1997-03-12 EP disclosed