Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395163 | 1.00 | HIF1A (0.48) | HIF1AL3MBTL1MAPTRAB9ALMNA | |
| SCHEMBL8395411 | 0.92 | HIF1A (0.48) | HIF1AMAPTPTGDR2TDP1ALDH1A1 | |
| SCHEMBL8395405 | 0.92 | HIF1A (0.48) | HIF1AMAPTPTGDR2TDP1ALDH1A1 | |
| SCHEMBL8369929 | 0.89 | HIF1A (0.50) | HIF1AL3MBTL1MAPTRAB9ALMNA | |
| SCHEMBL8398840 | 0.89 | HIF1A (0.50) | HIF1AL3MBTL1MAPTRAB9ALMNA | |
| SCHEMBL8369928 | 0.89 | HIF1A (0.50) | HIF1AL3MBTL1MAPTRAB9ALMNA | |
| SCHEMBL8399133 | 0.88 | HIF1A (0.51) | HIF1AL3MBTL1MAPTLMNAPTGDR2 | |
| SCHEMBL8399139 | 0.88 | HIF1A (0.51) | HIF1AL3MBTL1MAPTLMNAPTGDR2 | |
| SCHEMBL8398729 | 0.88 | HIF1A (0.50) | HIF1AL3MBTL1ALDH1A1SGMS2MEN1 | |
| SCHEMBL8398720 | 0.88 | HIF1A (0.50) | HIF1AL3MBTL1ALDH1A1SGMS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |