Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399139 | 1.00 | HIF1A (0.51) | HIF1APTGDR2KMT2AL3MBTL1GAA | |
| SCHEMBL8395405 | 0.89 | HIF1A (0.48) | HIF1APTGDR2MAPTHTTHPGD | |
| SCHEMBL8395411 | 0.89 | HIF1A (0.48) | HIF1APTGDR2MAPTHTTHPGD | |
| SCHEMBL8372750 | 0.88 | HIF1A (0.53) | HIF1APTGDR2KMT2AL3MBTL1LMNA | |
| SCHEMBL8398967 | 0.88 | HIF1A (0.53) | HIF1APTGDR2KMT2AL3MBTL1LMNA | |
| SCHEMBL8372751 | 0.88 | HIF1A (0.53) | HIF1APTGDR2KMT2AL3MBTL1LMNA | |
| SCHEMBL8395167 | 0.88 | HIF1A (0.48) | HIF1APTGDR2KMT2AL3MBTL1LMNA | |
| SCHEMBL8395163 | 0.88 | HIF1A (0.48) | HIF1APTGDR2KMT2AL3MBTL1LMNA | |
| SCHEMBL8621332 | 0.85 | HIF1A (0.60) | HIF1AGAAALDH1A1 | |
| SCHEMBL8621337 | 0.85 | HIF1A (0.60) | HIF1AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |