Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.42 |
| ▸ | CDK1 | P06493 | 3/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.42 |
| ▸ | GSK3A | P49840 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18754399 | 0.78 | MEN1 (0.64) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL622347 | 0.78 | KMT2A (0.59) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL16506422 | 0.77 | MEN1 (0.57) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL8856068 | 0.76 | LMNA (0.59) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL8396592 | 0.74 | MAPT (0.59) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL10780561 | 0.74 | MEN1 (0.52) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL18082985 | 0.74 | LMNA (0.57) | MEN1KMT2AMAPTKDM4EBLM | |
| SCHEMBL87693 | 0.73 | MAPT (0.50) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL29463681 | 0.73 | MAPT (0.50) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL30335572 | 0.73 | MAPT (0.50) | MEN1KMT2AMAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880135-A | ANTAGONIST ACTIVITY WITH RESPECT TO CORTICOTROPIN RELEASING HORMONE | SANOFI (FR) | 1999-03-09 | — | — | US | disclosed |
| EP-0833822-A1 | 4-PHENYLAMINOTHIAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000868-A1 | 4-PHENYLAMINOTHIAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1997-01-09 | — | — | WO | disclosed |
| US-4218369-A | FOR DYEING POLYACRYLONITRILE | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1980-08-19 | — | — | US | disclosed |