Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395245 | 1.00 | CYP2C9 (0.38) | CYP2C9TP53MAPTPOLBALDH1A1 | |
| SCHEMBL8395243 | 1.00 | CYP2C9 (0.38) | CYP2C9TP53MAPTPOLBALDH1A1 | |
| SCHEMBL8400407 | 0.96 | CYP2C9 (0.37) | CYP2C9TP53MAPTPOLBALDH1A1 | |
| SCHEMBL8400408 | 0.96 | CYP2C9 (0.37) | CYP2C9TP53MAPTPOLBALDH1A1 | |
| SCHEMBL8400406 | 0.96 | CYP2C9 (0.37) | CYP2C9TP53MAPTPOLBALDH1A1 | |
| SCHEMBL8398656 | 0.92 | CYP2C9 (0.46) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8398649 | 0.92 | CYP2C9 (0.46) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8398660 | 0.92 | CYP2C9 (0.46) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8019269 | 0.88 | CYP2C9 (0.43) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8019267 | 0.88 | CYP2C9 (0.43) | CYP2C9MAPTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5951913-A | Liquid crystal compositions comprising silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0630903-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5523439-A | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0696592-A1 | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |