⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28116807 | 0.81 | TSHR (0.35) | — | |
| SCHEMBL428952 | 0.72 | — | — | |
| SCHEMBL191827 | 0.72 | — | — | |
| SCHEMBL706872 | 0.72 | — | — | |
| SCHEMBL4279815 | 0.70 | — | — | |
| SCHEMBL4275869 | 0.70 | — | — | |
| SCHEMBL702420 | 0.70 | — | — | |
| SCHEMBL5949901 | 0.70 | — | — | |
| Ammonia Solution, Strong SCHEMBL20357888 | 0.70 | — | — | |
| Ammonia Solution, Strong SCHEMBL27762940 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963992-A2 | Method for preparation of tertiary-hydrocarbylsilyl compounds | DOW CORNING CORPORATION (US) | 1999-12-15 | — | — | EP | disclosed |
| US-5872274-A | Method for preparation of tertiary-hydrocarbylsilyl compounds | DOW CORNING CORPORATION (US) | 1999-02-16 | — | — | US | disclosed |