Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395804 | 0.95 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTL3MBTL1MAPK1MEN1 | |
| SCHEMBL8397897 | 0.95 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTLTA4HALDH1A1L3MBTL1 | |
| SCHEMBL8400489 | 0.92 | MAPK1 (0.44) | SMN1; SMN2MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL8396482 | 0.91 | HTT (0.42) | SMN1; SMN2MAPTLTA4HALDH1A1MEN1 | |
| SCHEMBL8396419 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL8398027 | 0.86 | HTT (0.42) | SMN1; SMN2MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL8397881 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL8396079 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL8395843 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTALDH1A1MEN1LMNA | |
| SCHEMBL8397040 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |