Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400489 | 0.96 | MAPK1 (0.44) | SMN1; SMN2MAPK1ATML3MBTL1LMNA | |
| SCHEMBL8395446 | 0.95 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPK1L3MBTL1MEN1LMNA | |
| SCHEMBL8397897 | 0.93 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPK1ATML3MBTL1LMNA | |
| SCHEMBL8396079 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPK1ATML3MBTL1LMNA | |
| SCHEMBL8396482 | 0.91 | HTT (0.42) | SMN1; SMN2MEN1LMNAKMT2AMAPT | |
| SCHEMBL8399138 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2ALTB4R2 | |
| SCHEMBL8398027 | 0.88 | HTT (0.42) | SMN1; SMN2MAPK1ATML3MBTL1MEN1 | |
| SCHEMBL8395843 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2ATMMEN1LMNAKMT2A | |
| SCHEMBL8399091 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPK1ATML3MBTL1MEN1 | |
| SCHEMBL8400187 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |