SCHEMBL8395461

SCHEMBL8395461

C=C(CC(C)(C)C)CC(O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11913512 0.87 TET2 (0.34) MEN1HTTKMT2ANPSR1
SCHEMBL819553 0.79 TSHR (0.31)
SCHEMBL822018 0.73 HSD17B10 (0.30)
SCHEMBL13036026 0.72 TET2 (0.32)
SCHEMBL2962912 0.72 MEN1 (0.33) MEN1HTTKMT2ANPSR1
SCHEMBL11790549 0.66
SCHEMBL11309012 0.66
SCHEMBL11990044 0.66 AR (0.32)
SCHEMBL9358443 0.64
SCHEMBL26370848 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0916352-A2 Use of polymers to inhibit the denaturation of absorbed proteins HÜLS AKTIENGESELLSCHAFT (DE) 1999-05-19 EP disclosed