Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8392487 | 1.00 | MEN1 (0.62) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL8395610 | 0.99 | HTT (0.62) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL8392818 | 0.96 | HTT (0.62) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL8393267 | 0.93 | HTT (0.65) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL8393973 | 0.92 | MEN1 (0.65) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL8393628 | 0.92 | MEN1 (0.65) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL8391394 | 0.91 | MEN1 (0.63) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL8396013 | 0.88 | LMNA (0.60) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL8396568 | 0.87 | HRH4 (0.56) | MEN1KMT2ASMN1; SMN2EPHX1HRH4 | |
| SCHEMBL8393364 | 0.87 | HRH4 (0.56) | MEN1KMT2ASMN1; SMN2EPHX1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |