Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | PREP | P48147 | 1/20 | 0.63 |
| ▸ | CTSK | P43235 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | PRCP | P42785 | 1/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.59 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.59 |
| ▸ | CTSB | P07858 | 1/20 | 0.59 |
| ▸ | CTSS | P25774 | 1/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247594 | 1.00 | CTRB1 (0.73) | CTRB1NPSR1TSHRKMT2AL3MBTL1 | |
| SCHEMBL8248799 | 1.00 | CTRB1 (0.73) | CTRB1NPSR1TSHRKMT2AL3MBTL1 | |
| SCHEMBL7265570 | 0.93 | CTRB1 (0.70) | CTRB1NPSR1TSHRKMT2AL3MBTL1 | |
| SCHEMBL9564582 | 0.93 | CTRB1 (0.70) | CTRB1NPSR1TSHRKMT2AL3MBTL1 | |
| SCHEMBL9243277 | 0.92 | CTRB1 (0.69) | CTRB1NPSR1TSHRKMT2AL3MBTL1 | |
| SCHEMBL31084237 | 0.92 | CTRB1 (0.69) | CTRB1NPSR1TSHRKMT2AL3MBTL1 | |
| SCHEMBL9243269 | 0.92 | CTRB1 (0.69) | CTRB1NPSR1TSHRKMT2AL3MBTL1 | |
| SCHEMBL10934560 | 0.91 | CTRB1 (0.68) | CTRB1NPSR1TSHRKMT2AL3MBTL1 | |
| SCHEMBL12234861 | 0.91 | CTRB1 (0.68) | CTRB1NPSR1TSHRKMT2AL3MBTL1 | |
| SCHEMBL10940771 | 0.91 | CTRB1 (0.68) | CTRB1NPSR1TSHRKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915908-A1 | DOLASTATIN PENTAPEPTIDE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-05-19 | — | — | EP | disclosed |
| US-5741892-A | Pentapeptides as antitumor agents | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-21 | — | — | US | disclosed |
| WO-1998004581-A1 | DOLASTATIN PENTAPEPTIDE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-05 | — | — | WO | disclosed |