Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8391122 | 0.98 | EPHX1 (0.46) | EPHX1LMNASMN1; SMN2HPGDCHRM2 | |
| SCHEMBL8391420 | 0.98 | EPHX1 (0.46) | EPHX1LMNASMN1; SMN2HPGDCHRM2 | |
| SCHEMBL8394724 | 0.95 | EPHX1 (0.40) | EPHX1LMNASMN1; SMN2HPGDCHRM2 | |
| SCHEMBL8393822 | 0.91 | — | — | |
| SCHEMBL4476046 | 0.87 | EPHX1 (0.53) | EPHX1SMN1; SMN2NAAA | |
| SCHEMBL8944571 | 0.85 | EPHX1 (0.56) | EPHX1SMN1; SMN2NAAA | |
| SCHEMBL4463801 | 0.85 | EPHX1 (0.56) | EPHX1SMN1; SMN2NAAA | |
| SCHEMBL8007105 | 0.83 | KLK7 (0.35) | EPHX1LMNASMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL8007113 | 0.83 | KLK7 (0.35) | EPHX1LMNASMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL8393592 | 0.83 | EPHX1 (0.49) | EPHX1SMN1; SMN2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |