Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 3/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007105 | 1.00 | KLK7 (0.35) | KLK7EPHX1CHRM4CHRM2CHRM5 | |
| SCHEMBL8007107 | 0.88 | EPHX1 (0.34) | KLK7EPHX1CHRM4CHRM2CHRM5 | |
| SCHEMBL8395658 | 0.83 | EPHX1 (0.43) | KLK7EPHX1CHRM4CHRM2CHRM5 | |
| SCHEMBL8394724 | 0.83 | EPHX1 (0.40) | KLK7EPHX1CHRM4CHRM2CHRM5 | |
| SCHEMBL1472866 | 0.82 | LMNA (0.43) | KLK7TDP1KDM4ELMNA | |
| SCHEMBL3744195 | 0.82 | LMNA (0.43) | KLK7TDP1KDM4ELMNA | |
| SCHEMBL8391122 | 0.81 | EPHX1 (0.46) | EPHX1CHRM4CHRM2CHRM5CHRM1 | |
| SCHEMBL8391420 | 0.81 | EPHX1 (0.46) | EPHX1CHRM4CHRM2CHRM5CHRM1 | |
| SCHEMBL8393822 | 0.79 | — | — | |
| SCHEMBL28447126 | 0.73 | ESR2 (0.42) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994177-A2 | Multifunctional and/or multi-aroma imparting, multisectional, multiwick candles; kits for preparing same; processes for preparing same and processes for using same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2000-04-19 | — | — | EP | disclosed |