Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 8/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9219185 | 0.97 | KDM4E (0.39) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL595080 | 0.67 | — | — | |
| SCHEMBL14434506 | 0.67 | — | — | |
| SCHEMBL9228117 | 0.67 | TSHR (0.33) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL1089229 | 0.65 | EPHX1 (0.43) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL3668939 | 0.65 | — | — | |
| SCHEMBL1170371 | 0.65 | TP53 (0.52) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL1079175 | 0.65 | — | — | |
| SCHEMBL22227354 | 0.65 | TP53 (0.52) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL10012157 | 0.65 | TP53 (0.52) | EPHX1TP53KDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0615978-B1 | Peptide derivatives of the boronic acid having protease inhibiting activity, process for their production and pharmaceutical compositions comprising them | ADIR (FR) | 1999-05-12 | — | — | EP | disclosed |
| US-5444049-A | Antithrombotic agents | ADIR ET COMPAGNIE (FR) | 1995-08-22 | — | — | US | disclosed |
| EP-0615978-A1 | Peptide derivatives of the boronic acid having protease inhibiting activity, process for their production and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 1994-09-21 | — | — | EP | disclosed |