Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332947 | 0.83 | ALDH1A1 (0.57) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL3712422 | 0.83 | ALDH1A1 (0.57) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL6330365 | 0.83 | ALDH1A1 (0.57) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL738198 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL762984 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL5778346 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL13912231 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL2115037 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL3054776 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2PKMCYP3A4CYP2C19GAA | |
| SCHEMBL8395972 | 0.79 | ALDH1A1 (0.42) | SMN1; SMN2GAAKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |