Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12502444 | 0.77 | PTPN1 (0.38) | PTPN1IDO1GAASMN1; SMN2BRD4 | |
| SCHEMBL18753027 | 0.75 | PTPN1 (0.41) | PTPN1IDO1GAASMN1; SMN2BRD4 | |
| SCHEMBL16871509 | 0.72 | KDM4E (0.41) | GAASMN1; SMN2BRD4KDM4EALDH1A1 | |
| SCHEMBL28770003 | 0.72 | HTR2A (0.34) | PTPN1IDO1GAASMN1; SMN2BRD4 | |
| SCHEMBL20260086 | 0.71 | PTPN1 (0.38) | PTPN1IDO1GAASMN1; SMN2BRD4 | |
| SCHEMBL13807152 | 0.71 | PTPN1 (0.38) | PTPN1IDO1GAASMN1; SMN2BRD4 | |
| SCHEMBL8392735 | 0.68 | IDO1 (0.36) | PTPN1IDO1GAASMN1; SMN2BRD4 | |
| SCHEMBL21669400 | 0.68 | GAA (0.35) | PTPN1IDO1GAASMN1; SMN2BRD4 | |
| SCHEMBL24360481 | 0.64 | OPRL1 (0.39) | PTPN1GAASMN1; SMN2BRD4MAPK1 | |
| SCHEMBL15430414 | 0.64 | PTPN1 (0.41) | PTPN1IDO1GAASMN1; SMN2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915653-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997049287-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | disclosed |