Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 3/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28770003 | 0.83 | HTR2A (0.34) | GAAALOX12LMNAMEN1MAPT | |
| SCHEMBL18753027 | 0.72 | PTPN1 (0.41) | GAAALOX12MEN1MAPTKMT2A | |
| SCHEMBL12502444 | 0.70 | PTPN1 (0.38) | GAAALOX12LMNAMEN1MAPT | |
| SCHEMBL8395949 | 0.68 | PTPN1 (0.37) | GAAMAPTKDM4EALDH1A1BRD4 | |
| SCHEMBL27112146 | 0.68 | ALDH1A1 (0.59) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13807152 | 0.64 | PTPN1 (0.38) | GAAMEN1MAPTKMT2ABRD4 | |
| SCHEMBL20260086 | 0.64 | PTPN1 (0.38) | GAAALOX12LMNAMEN1MAPT | |
| SCHEMBL25559769 | 0.63 | ALDH1A1 (0.50) | GAAALOX12LMNAMEN1MAPT | |
| SCHEMBL7498201 | 0.63 | LMNA (0.49) | ALOX12LMNAMEN1MAPTKMT2A | |
| SCHEMBL15430414 | 0.62 | PTPN1 (0.41) | GAAALOX12MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020026162-A1 | PROCESS FOR THE MULTISTEP CONTINUOUS-FLOW PREPARATION OF FLIBANSERIN | RICHTER GEDEON NYRT. (HU) | 2020-02-06 | — | — | WO | disclosed |