Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.80 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.77 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8944690 | 0.94 | PPARG (0.71) | PPARGAGTR1AGTR2 | |
| SCHEMBL8393405 | 0.91 | PPARG (0.84) | PPARGAGTR1AGTR2 | |
| SCHEMBL8396958 | 0.89 | PPARG (1.00) | PPARGAGTR1AGTR2 | |
| SCHEMBL8396181 | 0.88 | PPARG (0.76) | PPARGAGTR1AGTR2 | |
| SCHEMBL8393379 | 0.88 | PPARG (0.76) | PPARGAGTR1AGTR2 | |
| SCHEMBL8392354 | 0.88 | PPARG (0.76) | PPARGAGTR1AGTR2 | |
| SCHEMBL8917758 | 0.88 | PPARG (0.72) | PPARGAGTR1AGTR2 | |
| SCHEMBL8392419 | 0.87 | PPARG (0.74) | PPARGAGTR1AGTR2 | |
| SCHEMBL7021447 | 0.87 | AGTR1 (1.00) | PPARGAGTR1AGTR2 | |
| SCHEMBL8391717 | 0.87 | PPARG (0.71) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |