Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397517 | 0.89 | ALDH1A1 (0.54) | ALDH1A1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL8761756 | 0.88 | ALDH1A1 (0.53) | ALDH1A1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL8397510 | 0.88 | ALDH1A1 (0.69) | ALDH1A1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL8395766 | 0.88 | ALDH1A1 (0.48) | ALDH1A1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL8393774 | 0.87 | ALDH1A1 (0.60) | ALDH1A1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL8392739 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL8034242 | 0.83 | HPGD (0.47) | ALDH1A1HSD17B10KDM4ENPSR1L3MBTL1 | |
| SCHEMBL8381158 | 0.82 | ALDH1A1 (0.78) | ALDH1A1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL8395936 | 0.81 | KDM4E (0.49) | ALDH1A1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL8762207 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HSD17B10MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777663-B1 | USE OF SUBSTITUTED 6-AMINO-4H-PYRANS | BAYER AG (DE) | 1999-05-26 | — | — | EP | claimed |