Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400557 | 0.93 | SMN1; SMN2 (0.41) | AKR1B1SMN1; SMN2LMNATP53TSHR | |
| SCHEMBL8395199 | 0.93 | SMN1; SMN2 (0.43) | AKR1B1SMN1; SMN2P2RX3NPC1TSHR | |
| SCHEMBL8401802 | 0.91 | SMN1; SMN2 (0.38) | AKR1B1SMN1; SMN2TP53POLB | |
| SCHEMBL8397933 | 0.91 | SMN1; SMN2 (0.39) | AKR1B1SMN1; SMN2TSHR | |
| SCHEMBL8395933 | 0.91 | SMN1; SMN2 (0.51) | AKR1B1SMN1; SMN2 | |
| SCHEMBL8399334 | 0.90 | SMN1; SMN2 (0.40) | AKR1B1SMN1; SMN2LMNANPC1MAOB | |
| SCHEMBL8399094 | 0.90 | SMN1; SMN2 (0.39) | AKR1B1SMN1; SMN2LMNANPC1TSHR | |
| SCHEMBL8395400 | 0.90 | SMN1; SMN2 (0.39) | AKR1B1SMN1; SMN2P2RX3LMNATP53 | |
| SCHEMBL8399296 | 0.89 | SMN1; SMN2 (0.38) | AKR1B1SMN1; SMN2LMNATSHR | |
| SCHEMBL8396400 | 0.88 | MEN1 (0.38) | AKR1B1SMN1; SMN2LMNATP53MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |