Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395199 | 0.95 | SMN1; SMN2 (0.43) | SMN1; SMN2AKR1B1KDM4ETSHRMAPT | |
| SCHEMBL8397933 | 0.93 | SMN1; SMN2 (0.39) | SMN1; SMN2AKR1B1KDM4ETSHRMAPT | |
| SCHEMBL8396278 | 0.93 | AKR1B1 (0.41) | SMN1; SMN2AKR1B1MAOBTSHRLMNA | |
| SCHEMBL8395933 | 0.93 | SMN1; SMN2 (0.51) | SMN1; SMN2AKR1B1MAPTALDH1A1 | |
| SCHEMBL8399094 | 0.93 | SMN1; SMN2 (0.39) | SMN1; SMN2AKR1B1USP2KDM4ETSHR | |
| SCHEMBL8395400 | 0.93 | SMN1; SMN2 (0.39) | SMN1; SMN2AKR1B1LTB4R2MAOBLMNA | |
| SCHEMBL8401802 | 0.92 | SMN1; SMN2 (0.38) | SMN1; SMN2AKR1B1MAPTTP53NPSR1 | |
| SCHEMBL8399296 | 0.92 | SMN1; SMN2 (0.38) | SMN1; SMN2AKR1B1USP2TSHRMAPT | |
| SCHEMBL8396400 | 0.90 | MEN1 (0.38) | SMN1; SMN2AKR1B1LTB4R2MAOBMAPT | |
| SCHEMBL8400241 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2AKR1B1LTB4R2MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |