Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 15/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | FYN | P06241 | 1/20 | 0.61 |
| ▸ | GRB2 | P62993 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2121839 | 0.85 | HSD17B3 (0.69) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL4215955 | 0.83 | HSD17B3 (0.75) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL12433414 | 0.82 | HSD17B3 (0.73) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL536846 | 0.82 | HSD17B3 (1.00) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL27469537 | 0.82 | HSD17B3 (0.73) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL27989780 | 0.81 | HSD17B3 (0.73) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL27578191 | 0.81 | HSD17B3 (0.73) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL3762732 | 0.80 | HSD17B3 (1.00) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL4176874 | 0.80 | HSD17B3 (0.76) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL8396287 | 0.79 | HSD17B3 (0.69) | HSD17B3ALDH1A1GAAERAP1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872207-A | AMINOPROPYL SILICATE ON GLASS BEADS WITH PEPTIDES, CLEAVAGE WITH PROTEASE AND FLUORESECNCE | SANOFI PHARMACEUTICALS, INC. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5872207-A | AMINOPROPYL SILICATE ON GLASS BEADS WITH PEPTIDES, CLEAVAGE WITH PROTEASE AND FLUORESECNCE | SANOFI PHARMACEUTICALS, INC. (US) | 1999-02-16 | — | — | US | disclosed |