Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DVL1 | O14640 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371621 | 1.00 | HIF1A (0.64) | HIF1ASMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL8371619 | 1.00 | HIF1A (0.64) | HIF1ASMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL8399045 | 0.91 | HIF1A (0.57) | HIF1ASMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL8372646 | 0.91 | HIF1A (0.57) | HIF1ASMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL8372645 | 0.91 | HIF1A (0.57) | HIF1ASMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL8368226 | 0.90 | HIF1A (0.66) | HIF1ASMN1; SMN2L3MBTL1KMT2AMAPT | |
| SCHEMBL8368224 | 0.90 | HIF1A (0.66) | HIF1ASMN1; SMN2L3MBTL1KMT2AMAPT | |
| SCHEMBL8395953 | 0.89 | HIF1A (0.62) | HIF1ASMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL8395957 | 0.89 | HIF1A (0.62) | HIF1ASMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL8399228 | 0.89 | HIF1A (0.64) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |