Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.64 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399234 | 1.00 | HIF1A (0.64) | HIF1AMRGPRX4SLC6A2SLC6A4HTR1A | |
| SCHEMBL8369605 | 0.91 | HIF1A (0.57) | HIF1AMRGPRX4MAOBPARP10PARP15 | |
| SCHEMBL8369603 | 0.91 | HIF1A (0.57) | HIF1AMRGPRX4MAOBPARP10PARP15 | |
| SCHEMBL8368224 | 0.90 | HIF1A (0.66) | HIF1AMRGPRX4MAOBLMNA | |
| SCHEMBL8368226 | 0.90 | HIF1A (0.66) | HIF1AMRGPRX4MAOBLMNA | |
| SCHEMBL8399093 | 0.89 | HIF1A (0.62) | HIF1AMRGPRX4SLC6A2SLC6A4HTR1A | |
| SCHEMBL8399089 | 0.89 | HIF1A (0.62) | HIF1AMRGPRX4SLC6A2SLC6A4HTR1A | |
| SCHEMBL8371619 | 0.89 | HIF1A (0.64) | HIF1A | |
| SCHEMBL8371621 | 0.89 | HIF1A (0.64) | HIF1A | |
| SCHEMBL8396304 | 0.89 | HIF1A (0.64) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |