Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398077 | 0.91 | SMN1; SMN2 (0.72) | SMN1; SMN2TP53MEN1KMT2APOLQ | |
| SCHEMBL8395843 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2TP53MEN1KMT2ALMNA | |
| SCHEMBL8400187 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2TP53MEN1KMT2ALMNA | |
| SCHEMBL8399091 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2TP53MEN1KMT2ALMNA | |
| SCHEMBL8399169 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8400489 | 0.88 | MAPK1 (0.44) | SMN1; SMN2TP53LMNAALDH1A1TSHR | |
| SCHEMBL8396315 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2TP53MEN1KMT2APOLQ | |
| SCHEMBL8396079 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53LMNAALDH1A1TSHR | |
| SCHEMBL8395804 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2ALMNALTB4R2 | |
| SCHEMBL8399213 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |