Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.42 |
| ▸ | NQO2 | P16083 | 5/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396862 | 1.00 | CYP3A4 (0.46) | CYP3A4TSHRTDP1PTGS1PTGS2 | |
| SCHEMBL8827308 | 0.90 | PTGS1 (0.46) | CYP3A4TSHRTDP1PTGS1PTGS2 | |
| SCHEMBL8827302 | 0.90 | PTGS1 (0.46) | CYP3A4TSHRTDP1PTGS1PTGS2 | |
| SCHEMBL9343168 | 0.86 | PTGS1 (0.44) | PTGS1PTGS2NQO2ALOX5ESR1 | |
| SCHEMBL9343170 | 0.86 | PTGS1 (0.44) | PTGS1PTGS2NQO2ALOX5ESR1 | |
| SCHEMBL8827032 | 0.73 | PTGS1 (0.40) | PTGS1PTGS2NQO2ALOX5ESR1 | |
| SCHEMBL8827370 | 0.73 | GSK3B (0.41) | PTGS1PTGS2NQO2ALOX5ESR1 | |
| SCHEMBL8827023 | 0.73 | PTGS1 (0.40) | PTGS1PTGS2NQO2ALOX5ESR1 | |
| SCHEMBL8827373 | 0.73 | GSK3B (0.41) | PTGS1PTGS2NQO2ALOX5ESR1 | |
| SCHEMBL31185735 | 0.71 | TRPA1 (0.63) | CYP3A4TSHRTDP1TTRGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409069-B1 | Mesogenic polycyanates and polycyanamides and thermosets thereof | DOW CHEMICAL CO (US) | 1999-06-02 | — | — | EP | disclosed |
| EP-0409070-B1 | Mesogenic cyanite functional maleimides and thermosets thereof | DOW CHEMICAL CO (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5612479-A | Polyphenols containing mesogenic moieties as lateral substituents | THE DOW CHEMICAL COMPANY (US) | 1997-03-18 | — | — | US | disclosed |
| US-5470946-A | Products resulting from polymerizing or curing polycyanates containing mesogenic moieties as lateral substituents | THE DOW CHEMICAL COMPANY (US) | 1995-11-28 | — | — | US | disclosed |
| US-5442039-A | Rod-like mesogenic structures incorporated into polytriazine products; improved tensile strength, flexural strength | THE DOW CHEMICAL COMPANY (US) | 1995-08-15 | — | — | US | disclosed |
| US-5428125-A | Liquid crystalline | THE DOW CHEMICAL COMPANY (US) | 1995-06-27 | — | — | US | disclosed |
| US-5374769-A | Polycyanates containing mesogenic moieties as lateral substituents | THE DOW CHEMICAL COMPANY (US) | 1994-12-20 | — | — | US | disclosed |
| US-5248758-A | Curable composition | THE DOW CHEMICAL COMPANY (US) | 1993-09-28 | — | — | US | disclosed |
| US-5248757-A | Curable composition | THE DOW CHEMICAL COMPANY (US) | 1993-09-28 | — | — | US | disclosed |
| EP-0409070-A2 | Mesogenic cyanite functional maleimides and thermosets thereof | THE DOW CHEMICAL COMPANY (US) | 1991-01-23 | — | — | EP | disclosed |