Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15522076 | 0.88 | DPP4 (0.35) | DPP4SLC7A5 | |
| SCHEMBL17138262 | 0.78 | DPP4 (0.31) | DPP4 | |
| SCHEMBL8393454 | 0.76 | — | — | |
| SCHEMBL7068189 | 0.69 | CYP2D6 (0.35) | DPP4 | |
| SCHEMBL6610087 | 0.67 | SLC7A5 (0.34) | DPP4SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL16054205 | 0.67 | SLC7A5 (0.52) | DPP4SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL16863554 | 0.66 | SLC7A5 (0.50) | DPP4SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8410738 | 0.64 | — | — | |
| SCHEMBL24200992 | 0.63 | DPP4 (0.33) | DPP4 | |
| SCHEMBL2059189 | 0.62 | SLC7A5 (0.39) | SLC7A5SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915908-A1 | DOLASTATIN PENTAPEPTIDE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-05-19 | — | — | EP | disclosed |
| US-5741892-A | Pentapeptides as antitumor agents | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-21 | — | — | US | disclosed |
| WO-1998004581-A1 | DOLASTATIN PENTAPEPTIDE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-05 | — | — | WO | disclosed |