Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 4/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625177 | 0.89 | MMP2 (0.45) | MMP2KDM4EPTGS1PTGS2POLB | |
| SCHEMBL8399916 | 0.88 | MMP2 (0.44) | MMP2KDM4EPTGS1PTGS2POLB | |
| SCHEMBL9625193 | 0.85 | MMP2 (0.47) | MMP2KDM4EPTGS1PTGS2POLB | |
| SCHEMBL5315829 | 0.85 | MMP2 (0.49) | MMP2KDM4EPTGS1PTGS2POLB | |
| SCHEMBL9625259 | 0.82 | MMP2 (0.45) | MMP2KDM4EPTGS1PTGS2POLB | |
| SCHEMBL2120661 | 0.81 | MMP2 (0.49) | MMP2KDM4EPTGS1PTGS2POLB | |
| SCHEMBL9624732 | 0.81 | MMP2 (0.44) | MMP2KDM4EPTGS1PTGS2POLB | |
| SCHEMBL3337458 | 0.79 | KDM4E (0.65) | KDM4EPOLBL3MBTL1MAPTCYP1A2 | |
| SCHEMBL13439135 | 0.76 | MMP2 (0.46) | MMP2KDM4EPTGS1PTGS2POLB | |
| SCHEMBL10902995 | 0.76 | BCL2 (0.55) | MMP2KDM4EPTGS1PTGS2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962480-A | CONTAINING PYRAN-4-ONE OR PYRID-4-ONE RING | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | claimed |
| EP-0473764-A1 | METAL COMPLEXES | Hider, Robert Charles (GB) | 1992-03-11 | — | — | EP | claimed |
| WO-1991014664-A1 | METAL COMPLEXES | HIDER ROBERT CHARLES (GB) | 1991-10-03 | — | — | WO | claimed |
| US-5962480-A | CONTAINING PYRAN-4-ONE OR PYRID-4-ONE RING | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0838220-A1 | DRUG FOR AMELIORATING BRAIN DISEASES | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-29 | — | — | EP | disclosed |
| EP-0473764-A1 | METAL COMPLEXES | Hider, Robert Charles (GB) | 1992-03-11 | — | — | EP | disclosed |
| WO-1991014664-A1 | METAL COMPLEXES | HIDER ROBERT CHARLES (GB) | 1991-10-03 | — | — | WO | disclosed |