Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.57 |
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8391985 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL8393613 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL105543 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL77118 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL8391466 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL7310215 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL8391878 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL8396953 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL8395195 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL8392211 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |