Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.57 |
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8391985 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL8393613 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL77118 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL8391466 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL7310215 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL8391878 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL8396953 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL8395195 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL8397257 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL8392211 | 1.00 | EPHX1 (0.57) | EPHX1CASP2ZDHHC20ZDHHC2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530662-B2 | Pyridyltetrahydropyridines and pyridylpiperidines, and method of manufacturing them | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2013-09-10 | — | — | US | disclosed |
| EP-2426120-A1 | Pyridyltetrahydropyridines and pyridylpiperidines, and method of manufacturing them | Fujifilm Finechemicals Co., Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20100029947-A1 | Pyridyltetrahydropyridines and Pyridylpiperidines, and Method of Manufacturing Them | FUJIFILM FINECHEMICALS CO., LTD | 2010-02-04 | — | — | US | disclosed |
| US-7632950-B2 | Pyridyltetrahydropyridines and pyridylpiperidines and method of manufacturing them | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2009-12-15 | — | — | US | disclosed |
| US-20070093528-A1 | Pyridyltetrahydropyridines and pyridylpiperidines and method of manufacturing them | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2007-04-26 | — | — | US | disclosed |
| EP-1657240-A1 | PYRIDYLTETRAHYDROPYRIDINES, PYRIDYLPIPERIDINES, AND PROCESS FOR THE PRODUCTION OF BOTH | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2006-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029947-A1 | Pyridyltetrahydropyridines and Pyridylpiperidines, and Method of Manufacturing Them | QDPR, HRH4, HRH2 | EPHX1 1721/4885CASP2 2469/4885ZDHHC20 2025/4885 |
| US-20070093528-A1 | Pyridyltetrahydropyridines and pyridylpiperidines and method of manufacturing them | QDPR, HRH4, HRH2 | EPHX1 1672/4885CASP2 2746/4885ZDHHC20 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.