Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416923 | 0.90 | CYP2C19 (0.47) | ALDH1A1SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL8410579 | 0.87 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL7941116 | 0.86 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL7944844 | 0.83 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL8409728 | 0.82 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL8407764 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL7942593 | 0.79 | HIF1A (0.55) | ALDH1A1SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL7943247 | 0.79 | HSPA5 (0.58) | ALDH1A1SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL28492613 | 0.79 | HSPA5 (0.43) | ALDH1A1SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL10708543 | 0.76 | HSPA5 (0.56) | ALDH1A1SMN1; SMN2MAPK1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |