Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 20/20 | 0.63 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30646287 | 0.83 | SIGMAR1 (0.68) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6156054 | 0.78 | SIGMAR1 (1.00) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL6158171 | 0.76 | SIGMAR1 (1.00) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1238995 | 0.75 | SIGMAR1 (0.57) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8873221 | 0.72 | SIGMAR1 (0.54) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6681643 | 0.70 | SIGMAR1 (0.52) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8873537 | 0.69 | SIGMAR1 (1.00) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL19038543 | 0.68 | SIGMAR1 (0.50) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16139551 | 0.67 | SIGMAR1 (0.48) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6155761 | 0.65 | SIGMAR1 (0.67) | SIGMAR1ARKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |