Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.61 |
| ▸ | HTR2C | P28335 | 5/20 | 0.61 |
| ▸ | HTR2B | P41595 | 5/20 | 0.61 |
| ▸ | HTR1A | P08908 | 4/20 | 0.61 |
| ▸ | HTR1D | P28221 | 3/20 | 0.61 |
| ▸ | HTR6 | P50406 | 2/20 | 0.55 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | PARP1 | P09874 | 11/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688022 | 0.89 | MTNR1A (0.65) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL1567786 | 0.87 | HTR2A (0.61) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL7000777 | 0.86 | HTR2A (0.73) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL1567072 | 0.85 | HTR2A (0.59) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL8169370 | 0.84 | HTR2A (0.60) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL8169504 | 0.83 | HTR2A (0.59) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL31105674 | 0.81 | HTR2A (0.68) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL8169118 | 0.80 | MTNR1A (0.80) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL8169874 | 0.79 | MTNR1A (0.52) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL16926293 | 0.78 | MTNR1A (0.45) | HTR2AHTR2CHTR2BHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998461-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-12-07 | — | — | US | disclosed |