SCHEMBL8397363

SCHEMBL8397363

CCNCC(=O)NCC(=O)CC

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
MCL1 Q07820 1/20 0.35
TERT O14746 1/20 0.35
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.33
DPP4 P27487 1/20 0.31
GAA P10253 1/20 0.31
TP53 P04637 1/20 0.30
RECQL P46063 1/20 0.30
FAAH O00519 1/20 0.30
PSMB5 P28074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29312940 0.98 TDP1 (0.38) TDP1MCL1TERTKMT2AMEN1
SCHEMBL12035873 0.83
SCHEMBL21153346 0.81 MCL1 (0.48) MCL1TERTKMT2AMEN1POLB
SCHEMBL1790228 0.80
SCHEMBL8533512 0.80 MEN1 (0.52) TDP1MCL1KMT2AMEN1GAA
SCHEMBL24393751 0.79 MCL1 (0.37) TDP1MCL1TERTKMT2AMEN1
SCHEMBL1329568 0.79 FAAH (0.43) TDP1MCL1TERTKMT2AMEN1
Hydrochloric Acid SCHEMBL10795924 0.78 MCL1 (0.50) MCL1TERTKMT2AMEN1POLB
SCHEMBL16221910 0.78 FAAH (0.41) KMT2AMEN1GAARECQLFAAH
SCHEMBL21440848 0.77 MCL1 (0.35) TDP1MCL1TERTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024086826-A2 POLYPEPTIDYL LINKERS Quantum-Si Incorporated (US) 2024-04-25 WO disclosed