Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8397466 | 1.00 | HPGD (0.49) | HPGDLMNAALDH1A1GRIN2DGRIN3B | |
| SCHEMBL30862631 | 0.88 | GRIN2D (0.57) | HPGDLMNAALDH1A1GRIN2DGRIN3B | |
| SCHEMBL534274 | 0.88 | GRIN2D (0.57) | HPGDLMNAALDH1A1GRIN2DGRIN3B | |
| SCHEMBL1776974 | 0.88 | GRIN2D (0.57) | HPGDLMNAALDH1A1GRIN2DGRIN3B | |
| SCHEMBL534275 | 0.88 | GRIN2D (0.57) | HPGDLMNAALDH1A1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL28404034 | 0.86 | GRIN2D (0.58) | HPGDLMNAALDH1A1GRIN2DGRIN3B | |
| SCHEMBL27605451 | 0.79 | GRIN2D (0.49) | HPGDLMNAALDH1A1GRIN2DGRIN3B | |
| Bicarbonate SCHEMBL11884724 | 0.78 | ALDH1A1 (0.54) | HPGDLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL3447288 | 0.77 | ALDH1A1 (0.51) | HPGDLMNAALDH1A1GRIN2DGRIN3B | |
| SCHEMBL3447291 | 0.77 | ALDH1A1 (0.51) | HPGDLMNAALDH1A1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11269012-A | — | — | None | — | — | JP | disclosed |
| JP-10139603-A | — | — | None | — | — | JP | disclosed |
| JP-62294602-A | — | — | None | — | — | JP | disclosed |
| JP-8012507-A | — | — | None | — | — | JP | disclosed |
| JP-8012509-A | — | — | None | — | — | JP | disclosed |
| CN-116848070-B | Method for operating reverse osmosis membrane device, method for controlling slime, and water treatment device | KURITA WATER INDUSTRIES LTD. (JP) | 2026-05-26 | — | — | CN | disclosed |
| CN-116848070-A | Method for operating reverse osmosis membrane device | 栗田工业株式会社 | 2023-10-03 | — | — | CN | disclosed |
| CN-115667624-A | Method for suppressing generation of hydrogen sulfide in water tank | 栗田工业株式会社 | 2023-01-31 | — | — | CN | disclosed |
| JP-H11269012-A | EXTERMINATING AGENT FOR NOXIOUS MICROOORGANISM | SOMAR CORP | 1999-10-05 | — | — | JP | disclosed |
| JP-H10139603-A | INDUSTRIAL ANTIMICROBIAL | KURITA WATER IND LTD | 1998-05-26 | — | — | JP | disclosed |
| JP-H0812507-A | INDUSTRIAL MICROBICIDE | SOMAR CORP | 1996-01-16 | — | — | JP | disclosed |
| JP-H0812509-A | INDUSTRIAL MICROBICIDE | SOMAR CORP | 1996-01-16 | — | — | JP | disclosed |
| EP-0410609-A2 | Germicidal composition | SOMAR CORPORATION (JP) | 1991-01-30 | — | — | EP | disclosed |
| JP-S62294602-A | INDUSTRIAL GERMICIDE | SOMAR CORP | 1987-12-22 | — | — | JP | disclosed |
| JP-H00812509-A | — | — | 0001-01-01 | — | — | JP | disclosed |
| JP-H00812507-A | — | — | 0001-01-01 | — | — | JP | disclosed |