Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 12/20 | 0.48 |
| ▸ | RARB | P10826 | 11/20 | 0.48 |
| ▸ | RARA | P10276 | 10/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.48 |
| ▸ | GOT1 | P17174 | 1/20 | 0.48 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888168 | 0.91 | RARB (0.53) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8399151 | 0.91 | RARA (0.39) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8431715 | 0.91 | RARB (0.43) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8436675 | 0.90 | RARA (0.41) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8432429 | 0.90 | CYP3A4 (0.48) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8433865 | 0.89 | RARA (0.54) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8433276 | 0.89 | RARA (0.44) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8431871 | 0.89 | RARG (0.63) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8431926 | 0.89 | RARG (0.63) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8433281 | 0.88 | RARA (0.57) | RARGRARBRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877342-A | SKIN DISORDERS; RESPIRATORY SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUIES GALDERMA (FR) | 1999-03-02 | — | — | US | disclosed |